Leander ISD students earned top honors at the Texas Science & Engineering Fair, held March 28–29 in College Station. After advancing through regional competitions earlier this spring, these students showcased innovative research projects at the state-level event in several categories.

A team from Vista Ridge High School — Gabriella Thiakos, Rikita Veluru, and Aliza Azam — earned 3rd place for their project exploring potential treatments for Huntington’s Disease using microscopic organisms called C. elegans. The group was inspired by Veluru’s late grandmother, who had Parkinson’s Disease, another neurodegenerative disorder.

Motivated by the high cost and limited treatment options for these diseases, the students focused on identifying accessible and affordable prevention methods. “Currently, there is no cure for Huntington’s Disease, and prevention methods are often extremely expensive,” Veluru explained. “This motivated us to investigate alternatives that could be available to everyone.”

Their research showed promising results using microorganisms as a model, which could have broader impacts on the treatment of similar diseases. “Huntington’s Disease is closely related to other neurodegenerative conditions like Parkinson’s, Multiple Sclerosis, and ALS,” said Thiakos. “Using the same methodology as our experiment this year can allow for investigations into more supplemental treatments for all sorts of preventive and proactive medications.”

In addition to their biological research, the team is developing a coding program to analyze data from the microorganisms. This tool could be applied to future experiments across various scientific disciplines.

The students credited their success to strong support from their science teachers at Vista Ridge — Mrs. Kyle, Mr. Hoffman, and Mrs. Christman. “They’ve constantly encouraged us and provided both guidance and materials to make this experience meaningful,” Thiakos said. “The lessons we learned in their classes laid the foundation for our project.”

Even while completing important work, the students are able to have fun and make meaningful connections with each other and even students from other LISD schools along the way. “My favorite part of this project was working with my good friends, Gabriella and Aliza,” Veluru said. “We connected with others who share our passion for science, like Sahana from Vandegrift, who placed third at state in biochemistry.” 

Competing at the State Science Fair also gave the students access to other enriching opportunities like the Night at the ZACH event, a showcase of STEM programs and hands-on activities. “I love how the university we competed at and our school facilitated a place for us to enjoy ourselves and have fun while facing a serious academic competition,” Thiakos said. “The fair has been one of the most fun experiences I’ve had in my high school career, and I can’t wait to compete again next year.” 

Congratulations to all the #1LISD students who participated in the fair and placed in their respective categories!

Learn more about the Texas Science & Engineering Festival here

State Fair Science Fair Results: Leander ISD

Category: Cellular & Molecular Biology

🥇 1st Place: Jaxon Baharudin – Canyon Ridge MS 

Healing Eczema: Unveiling the Cellular Power of Natural Ingredients

“I chose this topic because several people I know personally suffer from eczema, and I’ve seen firsthand how challenging it can be,” said Jaxon Baharudin, a 6th-grade student at Canyon Ridge MS. “Eczema is one of the most common skin conditions globally, yet many people still struggle to find effective, accessible treatments. I wanted to create something that could make a real difference. It could be something that could potentially help not just those close to me, but many others dealing with this condition.”

“The support I received from my teachers at Canyon Ridge was essential,” Baharudin said. “They answered my questions about cellular and molecular biology and encouraged me to dig deeper into scientific concepts. Several of them even recommended specialists and resources that guided my research, helping me turn my idea into a well-developed project.”

Category: Behavior & Social Sciences

🥉 3rd Place: Gabriella Thiakos, Rikita Veluru, Aliza Azam – Vista Ridge HS

Implementation of the AM141 strain C. elegans model of Huntington’s Disease to introduce antioxidants and disaccharides in order to analyze the preventability and reduction of glutamine-40 accumulation through the observation of mobility and essential life

Category: Biochemistry

🥉 3rd Place: Sahana Pandey – Vandegrift HS

Targeting Cellular Senescence: In Silico Chemoinformatics Screening of Bioactive Compounds for Inducing Senolysis to Advance Geriatric Therapies

Category: Microbiology

🥉3rd Place: Maria VanLeeuwen – Vandegrift HS 

Investigating the Correlation between the Concentration of Calcium Chloride involved in Gene Insertion and its Effect on Transformation Efficiency

Category: Physics & Astronomy

🥉3rd Place: Siddharth Vazhkudai – Running Brushy MS 

AIM-BASE: AI-integrated model to predict the Energy consumption of Extraterrestrial Colonies